Journal Sciences News
Veterinary Clinics of North America: Food Animal Practice
Available online 24 April 2018
Can improving access to care help to eliminate malaria?
Publication date: Available online 24 April 2018
Source:The Lancet Author(s): Azra C Ghani
2127 April 2018
Effect of generalised access to early diagnosis and treatment and targeted mass drug administration on Plasmodium falciparum malaria in Eastern Myanmar: an observational study of a regional elimination programme
Publication date: Available online 24 April 2018
Source:The Lancet Author(s): Jordi Landier, Daniel M Parker, Aung Myint Thu, Khin Maung Lwin, Gilles Delmas, Fran
2127 April 2018
Orban not delivering health for Hungary
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): The Lancet
2127 April 2018
Sexual harassment and abusethe sinister underbelly
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): The Lancet
2127 April 2018
UK COPD treatment: failing to progress
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): The Lancet
2127 April 2018
Insecticide-resistant malaria vectors must be tackled
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Gerry F Killeen, Hilary Ranson
2127 April 2018
A snapshot of surgical outcomes and needs in Africa
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Anna J Dare, Bisola Onajin-Obembe, Emmanuel M Makasa
2127 April 2018
Macrolide resistance in yaws
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): David
2127 April 2018
The Lancet Commission on malaria eradication
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Ingrid Chen, Rebecca Cooney, Richard G A Feachem, Altaf Lal, Winnie Mpanju-Shumbusho
2127 April 2018
Social lobbying: a call to arms for public health
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Alessandro Demaio, Robert Marshall
2127 April 2018
Offline: The legacy and lessons of May '68
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Richard Horton
2127 April 2018
Claims of sexual harassment and assault threaten UN agency
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): John Zarocostas
2127 April 2018
Winnie Mpanju-Shumbusho: leader in the fight against malaria
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): John Zarocostas
2127 April 2018
Water and our planet
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Helen Bynum, Bill Bynum
2127 April 2018
Stories of shame
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Barry Lyons, Matthew Gibson, Luna Dolezal
2127 April 2018
Dame Beulah Rosemary Bewley
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Geoff Watts
2127 April 2018
Surgical surveillance in resource-poor settings
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Abi Beane, Duncan Wagstaff, Anuja Abayadeera, David Walker, Rashan Haniffa
2127 April 2018
Healthier lives for all Africans
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Robert Mash, Akye Essuman, Innocent Besigye, Olayinka Ayankogbe, Per Kallestrup, Jan De Maeseneer
2127 April 2018
The hepatitis B epidemic in China should receive more attention
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Shanquan Chen, Jun Li, Dan Wang, Hong Fung, Lai-yi Wong, Lu Zhao
2127 April 2018
Mesh augmentation for midline abdominal closure
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Tetsuji Fujita
2127 April 2018
Prophylactic repair to prevent midline incisional hernia
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Badri M Shrestha
2127 April 2018
Prophylactic mesh augmentation in midline laparotomy
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Manuel Jakob, Guido Beldi
2127 April 2018
Prevention of dementia by targeting risk factors
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Mika Kivim
2127 April 2018
Prevention of dementia by targeting risk factors
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Jason D Warren, Doris-Eva Bamiou
2127 April 2018
Prevention of dementia by targeting risk factors Authors' reply
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Gill Livingston, Andrew Sommerlad, Lon Schneider, Naaheed Mukadam, Sergi Costafreda
2127 April 2018
Department of Error
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130

2127 April 2018
Department of Error
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130

2127 April 2018
Department of Error
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130

2127 April 2018
Department of Error
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130

2127 April 2018
Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two factorial design trial
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Natacha Protopopoff, Jacklin F Mosha, Eliud Lukole, Jacques D Charlwood, Alexandra Wright, Charles D Mwalimu, Alphaxard Manjurano, Franklin W Mosha, William Kisinza, Immo Kleinschmidt, Mark Rowland Background Progress in malaria control is under threat by wide-scale insecticide resistance in malaria vectors. Two recent vector control products have been developed: a long-lasting insecticidal net that incorporates a synergist piperonyl butoxide (PBO) and a long-lasting indoor residual spraying formulation of the insecticide pirimiphos-methyl. We evaluated the effectiveness of PBO long-lasting insecticidal nets versus standard long-lasting insecticidal nets as single interventions and in combination with the indoor residual spraying of pirimiphos-methyl. Methods We did a four-group cluster randomised controlled trial using a two-by-two factorial design of 48 clusters derived from 40 villages in Muleba (Kagera, Tanzania). We randomly assigned these clusters using restricted randomisation to four groups: standard long-lasting insecticidal nets, PBO long-lasting insecticidal nets, standard long-lasting insecticidal nets plus indoor residual spraying, or PBO long-lasting insecticidal nets plus indoor residual spraying. Both standard and PBO nets were distributed in 2015. Indoor residual spraying was applied only once in 2015. We masked the inhabitants of each cluster to the type of nets received, as well as field staff who took blood samples. Neither the investigators nor the participants were masked to indoor residual spraying. The primary outcome was the prevalence of malaria infection in children aged 6 months to 14 years assessed by cross-sectional surveys at 4, 9, 16, and 21 months after intervention. The endpoint for assessment of indoor residual spraying was 9 months and PBO long-lasting insecticidal nets was 21 months. This trial is registered with ClinicalTrials.gov, number NCT02288637. Findings 7184 (680%) of 10
2127 April 2018
Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Bruce M Biccard, Thandinkosi E Madiba, Hyla-Louise Kluyts, Dolly M Munlemvo, Farai D Madzimbamuto, Apollo Basenero, Christina S Gordon, Coulibaly Youssouf, Sylvia R Rakotoarison, Veekash Gobin, Ahmadou L Samateh, Chaibou M Sani, Akinyinka O Omigbodun, Simbo D Amanor-Boadu, Janat T Tumukunde, Tonya M Esterhuizen, Yannick Le Manach, Patrice Forget, Abdulaziz M Elkhogia, Ryad M Mehyaoui, Eugene Zoumeno, Gabriel Ndayisaba, Henry Ndasi, Andrew K N Ndonga, Zipporah W W Ngumi, Ushmah P Patel, Daniel Zemenfes Ashebir, Akwasi A K Antwi-Kusi, Bernard Mbwele, Hamza Doles Sama, Mahmoud Elfiky, Maher A Fawzy, Rupert M Pearse Background There is a need to increase access to surgical treatments in African countries, but perioperative complications represent a major global health-care burden. There are few studies describing surgical outcomes in Africa. Methods We did a 7-day, international, prospective, observational cohort study of patients aged 18 years and older undergoing any inpatient surgery in 25 countries in Africa (the African Surgical Outcomes Study). We aimed to recruit as many hospitals as possible using a convenience sampling survey, and required data from at least ten hospitals per country (or half the surgical centres if there were fewer than ten hospitals) and data for at least 90% of eligible patients from each site. Each country selected one recruitment week between February and May, 2016. The primary outcome was in-hospital postoperative complications, assessed according to predefined criteria and graded as mild, moderate, or severe. Data were presented as median (IQR), mean (SD), or n (%), and compared using t tests. This study is registered on the South African National Health Research Database (KZ_2015RP7_22) and ClinicalTrials.gov (NCT03044899). Findings We recruited 11
2127 April 2018
Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Oriol Mitj
2127 April 2018
Malaria
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Elizabeth A Ashley, Aung Pyae Phyo, Charles J Woodrow Following unsuccessful eradication attempts there was a resurgence of malaria towards the end of the 20th century. Renewed control efforts using a range of improved tools, such as long-lasting insecticide-treated bednets and artemisinin-based combination therapies, have more than halved the global burden of disease, but it remains high with 445
Available online 17 April 2018
Multiple sclerosis
Publication date: 2127 April 2018
Source:The Lancet, Volume 391, Issue 10130 Author(s): Alan J Thompson, Sergio E Baranzini, Jeroen Geurts, Bernhard Hemmer, Olga Ciccarelli Multiple sclerosis continues to be a challenging and disabling condition but there is now greater understanding of the underlying genetic and environmental factors that drive the condition, including low vitamin D levels, cigarette smoking, and obesity. Early and accurate diagnosis is crucial and is supported by diagnostic criteria, incorporating imaging and spinal fluid abnormalities for those presenting with a clinically isolated syndrome. Importantly, there is an extensive therapeutic armamentarium, both oral and by infusion, for those with the relapsing remitting form of the disease. Careful consideration is required when choosing the correct treatment, balancing the side-effect profile with efficacy and escalating as clinically appropriate. This move towards more personalised medicine is supported by a clinical guideline published in 2018. Finally, a comprehensive management programme is strongly recommended for all patients with multiple sclerosis, enhancing health-related quality of life through advocating wellness, addressing aggravating factors, and managing comorbidities. The greatest remaining challenge for multiple sclerosis is the development of treatments incorporating neuroprotection and remyelination to treat and ultimately prevent the disabling, progressive forms of the condition.
Available online 17 April 2018
Healthy cities: key to a healthy future in China
Publication date: Available online 17 April 2018
Source:The Lancet Author(s): William Summerskill, Helena Hui Wang, Richard Horton
Available online 17 April 2018
The TsinghuaLancet Commission on Healthy Cities in China: unlocking the power of cities for a healthy China
Publication date: Available online 17 April 2018
Source:The Lancet Author(s): Jun Yang, Jos
Available online 17 April 2018
Spending on health and HIV/AIDS: domestic health spending and development assistance in 188 countries, 19952015
Publication date: Available online 17 April 2018
Source:The Lancet Author(s): Global Burden of Disease Health Financing Collaborator NetworkJoseph LDielemanAnnieHaakenstadAngelaMicahMarkMosesCristianaAbbafatiPawanAcharyaTara BallavAdhikariArs
Available online 16 April 2018
Trends in future health financing and coverage: future health spending and universal health coverage in 188 countries, 201640
Publication date: Available online 17 April 2018
Source:The Lancet Author(s): Global Burden of Disease Health Financing Collaborator NetworkJoseph LDielemanNafisSadatAngela YChangNancyFullmanCristianaAbbafatiPawanAcharyaArs
Available online 16 April 2018
Before the beginning: nutrition and lifestyle in the preconception period and its importance for future health
Publication date: Available online 16 April 2018
Source:The Lancet Author(s): Judith Stephenson, Nicola Heslehurst, Jennifer Hall, Danielle A J M Schoenaker, Jayne Hutchinson, Janet E Cade, Lucilla Poston, Geraldine Barrett, Sarah R Crozier, Mary Barker, Kalyanaraman Kumaran, Chittaranjan S Yajnik, Janis Baird, Gita D Mishra A woman who is healthy at the time of conception is more likely to have a successful pregnancy and a healthy child. We reviewed published evidence and present new data from low-income, middle-income, and high-income countries on the timing and importance of preconception health for subsequent maternal and child health. We describe the extent to which pregnancy is planned, and whether planning is linked to preconception health behaviours. Observational studies show strong links between health before pregnancy and maternal and child health outcomes, with consequences that can extend across generations, but awareness of these links is not widespread. Poor nutrition and obesity are rife among women of reproductive age, and differences between high-income and low-income countries have become less distinct, with typical diets falling far short of nutritional recommendations in both settings and especially among adolescents. Several studies show that micronutrient supplementation starting in pregnancy can correct important maternal nutrient deficiencies, but effects on child health outcomes are disappointing. Other interventions to improve diet during pregnancy have had little effect on maternal and newborn health outcomes. Comparatively few interventions have been made for preconception diet and lifestyle. Improvements in the measurement of pregnancy planning have quantified the degree of pregnancy planning and suggest that it is more common than previously recognised. Planning for pregnancy is associated with a mixed pattern of health behaviours before conception. We propose novel definitions of the preconception period relating to embryo development and actions at individual or population level. A sharper focus on intervention before conception is needed to improve maternal and child health and reduce the growing burden of non-communicable diseases. Alongside continued efforts to reduce smoking, alcohol consumption, and obesity in the population, we call for heightened awareness of preconception health, particularly regarding diet and nutrition. Importantly, health professionals should be alerted to ways of identifying women who are planning a pregnancy.
Available online 16 April 2018
Intervention strategies to improve nutrition and health behaviours before conception
Publication date: Available online 16 April 2018
Source:The Lancet Author(s): Mary Barker, Stephan U Dombrowski, Tim Colbourn, Caroline H D Fall, Natasha M Kriznik, Wendy T Lawrence, Shane A Norris, Gloria Ngaiza, Dilisha Patel, Jolene Skordis-Worrall, Falko F Sniehotta, R
1420 April 2018
Origins of lifetime health around the time of conception: causes and consequences
Publication date: Available online 16 April 2018
Source:The Lancet Author(s): Tom P Fleming, Adam J Watkins, Miguel A Velazquez, John C Mathers, Andrew M Prentice, Judith Stephenson, Mary Barker, Richard Saffery, Chittaranjan S Yajnik, Judith J Eckert, Mark A Hanson, Terrence Forrester, Peter D Gluckman, Keith M Godfrey Parental environmental factors, including diet, body composition, metabolism, and stress, affect the health and chronic disease risk of people throughout their lives, as captured in the Developmental Origins of Health and Disease concept. Research across the epidemiological, clinical, and basic science fields has identified the period around conception as being crucial for the processes mediating parental influences on the health of the next generation. During this time, from the maturation of gametes through to early embryonic development, parental lifestyle can adversely influence long-term risks of offspring cardiovascular, metabolic, immune, and neurological morbidities, often termed developmental programming. We review periconceptional induction of disease risk from four broad exposures: maternal overnutrition and obesity; maternal undernutrition; related paternal factors; and the use of assisted reproductive treatment. Studies in both humans and animal models have demonstrated the underlying biological mechanisms, including epigenetic, cellular, physiological, and metabolic processes. We also present a meta-analysis of mouse paternal and maternal protein undernutrition that suggests distinct parental periconceptional contributions to postnatal outcomes. We propose that the evidence for periconceptional effects on lifetime health is now so compelling that it calls for new guidance on parental preparation for pregnancy, beginning before conception, to protect the health of offspring.
1420 April 2018
Closing the gender pay gap: when and how?
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): The Lancet
1420 April 2018
The General Medical Council has lost its way
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): The Lancet
1420 April 2018
South Africa sliding backwards
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): The Lancet
1420 April 2018
Skeletal muscle channelopathy: a new risk for sudden infant death syndrome
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): Stephen C Cannon
1420 April 2018
A call to action: improving women's, children's, and adolescents' health in the Muslim world
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): Amina J Mohammed
1420 April 2018
Thresholds for safer alcohol use might need lowering
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): Jason Connor, Wayne Hall
1420 April 2018
The social sciences, humanities, and health
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): Martyn Pickersgill, Sarah Chan, Gill Haddow, Graeme Laurie, Devi Sridhar, Steve Sturdy, Sarah Cunningham-Burley
1420 April 2018
Public Health Science Conference: a call for abstracts
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): May C I van Schalkwyk, Robert W Aldridge

Offline: A sea of suffering
Publication date: 1420 April 2018
Source:The Lancet, Volume 391, Issue 10129 Author(s): Richard Horton
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