Journal Sciences News
Veterinary Clinics of North America: Food Animal Practice
Available online 18 January 2018
Department of Error
Publication date: Available online 19 January 2018
Source:The Lancet

Available online 18 January 2018
A new powerful drug to combat river blindness
Publication date: Available online 18 January 2018
Source:The Lancet Author(s): Michel Boussinesq
Available online 18 January 2018
Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial
Publication date: Available online 18 January 2018
Source:The Lancet Author(s): Nicholas O Opoku, Didier K Bakajika, Eric M Kanza, Hayford Howard, Germain L Mambandu, Amos Nyathirombo, Maurice M Nigo, Kambale Kasonia, Safari L Masembe, Mupenzi Mumbere, Kambale Kataliko, Jemmah P Larbelee, Mawolo Kpawor, Kpehe M Bolay, Fatorma Bolay, Simon K Attah, Michel Vaillant, Christine M Halleux, Annette C Kuesel Background The morbidity and socioeconomic effects of onchocerciasis, a parasitic disease that is primarily endemic in sub-Saharan Africa, have motivated large morbidity and transmission control programmes. Annual community-directed ivermectin treatment has substantially reduced prevalence. Elimination requires intensified efforts, including more efficacious treatments. We compared parasitological efficacy and safety of moxidectin and ivermectin. Methods This double-blind, parallel group, superiority trial was done in four sites in Ghana, Liberia, and the Democratic Republic of the Congo. We enrolled participants (aged
1319 January 2018
Progress in clinical research in surgery and IDEAL
Publication date: Available online 18 January 2018
Source:The Lancet Author(s): Peter McCulloch, Joshua Feinberg, Yiannis Philippou, Angelos Kolias, Sean Kehoe, Gillian Lancaster, Jenny Donovan, Tatjana Petrinic, Riaz Agha, Christopher Pennell The quality of clinical research in surgery has long attracted criticism. High-quality randomised trials have proved difficult to undertake in surgery, and many surgical treatments have therefore been adopted without adequate supporting evidence of efficacy and safety. This evidence deficit can adversely affect research funding and reimbursement decisions, lead to slow adoption of innovations, and permit widespread adoption of procedures that offer no benefit, or cause harm. Improvement in the quality of surgical evidence would therefore be valuable. The Idea, Development, Exploration, Assessment, and Long-term Follow-up (IDEAL) Framework and Recommendations specify desirable qualities for surgical studies, and outline an integrated evaluation pathway for surgery, and similar complex interventions. We used the IDEAL Recommendations to assess methodological progress in surgical research over time, assessed the uptake and influence of IDEAL, and identified the challenges to further methodological progress. Comparing studies from the periods 200004 and 201014, we noted apparent improvement in the use of standard outcome measures, adoption of Consolidated Standards of Reporting Trials (CONSORT) standards, and assessment of the quality of surgery and of learning curves, but no progress in the use of qualitative research or reporting of modifications during procedure development. Better education about research, integration of rigorous evaluation into routine practice and training, and linkage of such work to awards systems could foster further improvements in surgical evidence. IDEAL has probably contributed only slightly to the improvements described to date, but its uptake is accelerating rapidly. The need for the integrated evaluation template IDEAL offers for surgery and other complex treatments is becoming more widely accepted.
1319 January 2018
Children and social media
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): The Lancet
1319 January 2018
A new vaccine for typhoid control
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): The Lancet
1319 January 2018
Sanctioning the most vulnerablea failed foreign policy
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): The Lancet
1319 January 2018
Tranexamic acid: is it about time?
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): David J Dries
1319 January 2018
Nutrition in the ICU: sometimes route does matter
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Lisa Van Dyck, Michael P Casaer
1319 January 2018
Oral fexinidazole for human African trypanosomiasis
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Fran
1319 January 2018
Scaling up integration of health services
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Erin K Ferenchick, Kumanan Rasanathan, Nuria Toro Polanco, Olga Bornemisza, Edward Kelley, Viviana Mangiaterra
1319 January 2018
Chronic liver disease: scavenger hunt for novel therapies
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Daniel A Patten, Shishir Shetty
1319 January 2018
Offline: Time to act on minimum unit pricing of alcohol
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Richard Horton
1319 January 2018
Malaysia: a refugee conundrum
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Adam Bemma
1319 January 2018
Iranian protests and Rouhanicare
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Sharmila Devi
1319 January 2018
Doctors disagree with proposed medical bill in India
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Patralekha Chatterjee
1319 January 2018
A literary pain scale
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Ann Jurecic
1319 January 2018
Truth and information
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Marco De Ambrogi
1319 January 2018
Man-made disaster
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Michael Marmot
1319 January 2018
Natalia Kanem: lifelong advocate for women's health and rights
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): John Zarocostas
1319 January 2018
Changing minds about changing behaviour
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Theresa M Marteau
1319 January 2018
Shila Kaur
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Andrew Green
1319 January 2018
Saving the Joint Comprehensive Plan of Action: full of hope or just hopeless?
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Masoud Mozafari
1319 January 2018
Treaty to prohibit nuclear weapons and Germany's global health responsibility
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Kayvan Bozorgmehr, Eva-Maria Schwienhorst-Stich
1319 January 2018
Singapore should play a strong leadership role in global health
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Tikki Pang
1319 January 2018
Questions regarding the CONCERN trial
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Ricky D Turgeon
1319 January 2018
Questions regarding the CONCERN trial Authors' reply
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Francis K L Chan, Jessica Y L Ching, Yee Kit Tse, Moe H Kyaw
1319 January 2018
Translation of the link between cancer and obesity to patients
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Dalia Abdulhussein, Elham Amin
1319 January 2018
GRECCAR2 trial: details worthy of more attention
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Huixun Jia, Yun Guan, Ji Zhu
1319 January 2018
GRECCAR2 trial: details worthy of more attention Authors' reply
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Eric Rullier, V
1319 January 2018
Pitfalls of the healthy vaccinee effect
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Salaheddin M Mahmud, Christiaan H Righolt
1319 January 2018
Pitfalls of the healthy vaccinee effect Authors' reply
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Helen Petousis-Harris, Janine Paynter, Jane Morgan, Peter Saxton, Felicity Goodyear-Smith, Steven Black
1319 January 2018
Department of Error
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116

1319 January 2018
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40
1319 January 2018
Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2)
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Jean Reignier, Julie Boisram
1319 January 2018
Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Victor Kande Betu Ku Mesu, Wilfried Mutombo Kalonji, Cl
1319 January 2018
Thalassaemia
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): Ali T Taher, David J Weatherall, Maria Domenica Cappellini Inherited haemoglobin disorders, including thalassaemia and sickle-cell disease, are the most common monogenic diseases worldwide. Several clinical forms of
612 January 2018
Hyperparathyroidism
Publication date: 1319 January 2018
Source:The Lancet, Volume 391, Issue 10116 Author(s): John P Bilezikian, Leonardo Bandeira, Aliya Khan, Natalie E Cusano Primary hyperparathyroidism is a common endocrine disorder of calcium metabolism characterised by hypercalcaemia and elevated or inappropriately normal concentrations of parathyroid hormone. Almost always, primary hyperparathyroidism is due to a benign overgrowth of parathyroid tissue either as a single gland (80% of cases) or as a multiple gland disorder (1520% of cases). Primary hyperparathyroidism is generally discovered when asymptomatic but the disease always has the potential to become symptomatic, resulting in bone loss and kidney stones. In countries where biochemical screening tests are not common, symptomatic primary hyperparathyroidism tends to predominate. Another variant of primary hyperparathyroidism has been described in which the serum calcium concentration is within normal range but parathyroid hormone is elevated in the absence of any obvious cause. Primary hyperparathyroidism can be cured by removal of the parathyroid gland or glands but identification of patients who are best advised to have surgery requires consideration of the guidelines that are regularly updated. Recommendations for patients who do not undergo parathyroid surgery include monitoring of serum calcium concentrations and bone density.
612 January 2018
The NHS at 70 and Alma-Ata at 40
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): The Lancet
612 January 2018
Vision quest: gene therapy for inherited vision loss
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115

612 January 2018
Tuberculosis: criteria for global leadership?
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): The Lancet
612 January 2018
Personalised medicine in the UK
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): The Lancet
612 January 2018
Last nail in the coffin for PCI in stable angina?
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): David L Brown, Rita F Redberg
612 January 2018
A SENIOR moment? Bare-metal stents in elderly patients
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): Robert T Gerber, Anthony H Gershlick
612 January 2018
Surgery versus endoscopy for patients with infected pancreatic necrosis
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): Douglas G Adler
612 January 2018
Circadian rhythm and ischaemiareperfusion injury
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): Thomas Bochaton, Michel Ovize
612 January 2018
Renewing the focus on health care for sexually assaulted children and adolescents
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): Rachel Jewkes
612 January 2018
The polio endgame: securing a world free of all polioviruses
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): Michel Zaffran, Michael McGovern, Reza Hossaini, Rebecca Martin, Jay Wenger
612 January 2018
Offline: From 1918 to 2018the lessons of influenza
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): Richard Horton

Syria: 7 years into a civil war
Publication date: 612 January 2018
Source:The Lancet, Volume 391, Issue 10115 Author(s): Sharmila Devi
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